Introduction: This study investigated the effectiveness of a group-based 8-week intervention, Mindfulness-integrated Cognitive Behavior Therapy (MiCBT), to decrease health anxiety and death obsession in Patients with COVID-19.
 Methods: Participants (n = 30, aged 25–45) were randomized to two groups (MiCBT), and control. Outcomes were assessed at pre-, postintervention and at 2-month follow-up. The Secondary outcome measures were the Short Health Anxiety Inventory (SHAI) and the Death Obsession Scale (DOS).
Results: The MiCBT intervention significantly reduced health anxiety and death obsession scale scores at posttreatment and the gains were maintained at 2-month follow-up (p < 0.0001).
Conclusion: The results support the effectiveness of MiCBT in creating rapid and sustainable reduction of health anxiety and death obsession in Patients with COVID-19. These promising results support the feasibility and acceptability implementation of this intervention in patients with COVID-19 in Iran.