Abstract Background: misuse of antibiotics is one of the issues that can have different health and economic consequences. the purpose of this study was to investigate the history of using antibiotics, the advantages and disadvantages of overuse of antibiotics and, finally, the benefits of taking antibiotic tygesicline. . the aim of the present study was to identify new antibiotic-based antibiotics with an emphasis on tygesicline. Research method: this research is a descriptive and documentary review that is gathered by referring to print and electronic resources printed between 2010 and 2018 through scientific databases such as Pubmed, Sciencediret, Springer, Google Scholar. . Results: Several antibiotics have been used to inhibit growth and eliminate germs, but the development of resistance and the emergence of side effects have severely restricted the use of these factors in recent years, the efficacy of using tygesicline antibiotics in the treatment of infectious diseases has been proven. Discussion and Conclusion: The use of antibiotic tygesicline as one of the effective medicines in the treatment of antibiotics has increased the current pharmacological effects of increased sensitivity, selectivity and multidimensional capacity. this article explores the benefits and limitations of taking tactile antibiotics.