Introduction: Eempowerment is a new approach for survival organization in a competitive environment. In order to increase quality and quantity of services which introduce in health care organizations, dimensions of structure in it could be effective on empowering of employees.

Aim: The relationship between dimensions of structure of organizational and employees’ psychological empowerment in Mashhad University of Medical Sciences was the aim of this study.

Method: This study was a descriptive study that in (2009-2011) in Mashhad University of Medical Sciences was done. All of employees (n = 600) in different departments in university (all of teaching hospitals, faculties, health centers and staff deputies) were samples that selected by randomly stratified sampling. For data gather two standardized questionnaires were used psychological empowerment’s (Spreitzer) and organizational structure’s (Stephen Robbins) that Cronbach’s alpha coefficient was for the first (89/0% ) and for dimensions of organizational structure was between (0/71%) to (0/83%).For analysis was used Spearman’s Rank Order correlation coefficient and Kolmogrov Smirnov test by SPSS 11 software.

Results: Analysis data showed that there is not any significant relationship between the dimensions of organizational structure and employee empowerment(p=0.28 and r=0.046). Between career and level of education, formalization and sense of meaningfulness of work, formalization and feeling of competence there is a significant relationship (p<0.05).

Conclusion: Aaccording to results suggests that managers applying strategies for motivating employees who have higher education degree and also, for increasing their empowerment change work environment by job enlargement and enrichment.