Introduction: The necessary requirements of nursing information systems are nursing classification systems that they have been used for classifying of nursing diagnoses, interventions, and outcomes. But, it is important how these classification systems used in nursing information system.

Aim: The aim of this study was application of classification systems in nursing classification systems.

 Method:This study was an integrative review of literatures that web sites such as the Science Direct, CINAHL, Pubmed, Scirus and Google Scholar databases searched for key words: nursing, nursing classification systems, nursing information system, nursing documentation, and nursing informatics.143 articles from 1998 to 2012 were founded. After the initial study, 42 articles were suitable for coating purposes of this study. The inclusion criteria were the relevancy of the articles to the objectives of the study. The content analysis and synthesis of the literature led to organizing this article.

Results: The most important applications of classification systems in nursing classification systems were the classifying of nursing-related entities, evidence based decision making, analyzing of the care patterns, building a theoretical body and improving the nursing knowledge. In addition, the classified information could be used for educating, researching, managing, and developing of care approaches and improving the nursing communications.

Conclusion: Regarding Classification systems are essential for nursing classification systems should be considered needs of different nursing groups.