Introduction: Patient safety defines as protection the patient from medical error and iatrogenic event. Many factors cause the patient safety events. One of them is nurse- physician interaction, because any obstacles of this can result in disorder of teamwork and there for put in danger patient safety and quality of care.

Aim: The aim was to assess the patient safety events and it’s correlation with nurse - physician interaction from nurses’ view point.

Method: This is a descriptive cross sectional study on 200 nurses on Tehran University of medical science hospitals. Stratified sampling was used. A three parts questionnaire (demographic data, patient safety events and nurse - physician interaction) was used. Internal consistency reliability (Cronbach’s alpha) was (α=0.8) for patient safety events indicators and it was (α=0.74) for professional interaction. Patient safety events frequencies were identified during last 3 months and then, their relationship with nurse-physician interaction was assessed. Data were analyzed using SPSS 14, and Spearman correlation coefficient, χ2 and multiple regressions were used.

Results: The nurses reported the most common patient safety events were medication errors (38.5%) skin and neuromuscular damage (36.7%) and post-operative (16%).And the less common patient safety events were patient’s death following errors(1%) and leaving objects in patient’s body(1%). Majority of nurses rated their interaction with physician good (65.5%). There were significant reverse correlations between patient safety events and nurse- physician interaction (p=0.001, r = -0.274).It means that if interaction between nurse- physician is good, patient safety events will be decrease.

Conclusion: Since patient safety events can be related to nurse -physician interaction, improving the nurse -physician interaction as a related factor in patient safety should be consider more seriously.