Introduction: Manpower is very important in improving the performance of the hospital so that this organization cannot succeed without the effort and commitment of its staff. Organizational commitment refers to employees' beliefs, values and beliefs about staying in the organization. The aim of this study was to investigate the organizational commitment of nurses and related factors. Methods: This is a systematic study. Major international and national databases including Google Scholar, PubMed Scopus, Science Direct, Cinahl, SID, Iranmedex, and Magiran were search completely to identify the articles published from 2011 to 2021 on the topic of interest among Iranian nurses. The keywords organizational commitment, nurse, was used in English and Persian sources. After evaluating the entry and quality criteria of the articles, 26 papers were recognized as eligible and entered into the study. Results: The results of extracting the findings of the articles showed that 12% of the nurses' organizational commitment studies report a high level, 50% a medium level and 38% of the studies did not report a level of organizational commitment. Also, various individual and organizational factors affect the organizational commitment of nurses. Conclusion: Given that the most important and valuable asset of the organization is manpower. Therefore, trying to develop commitment in employees is an important issue that managers should pay attention to. Managers, through actions such as empowerment and creating a positive ethical atmosphere, provide the basis for interactions based on social mechanisms in the form of mutual trust and respect to increase nurses' organizational commitment and improve the quality of nursing services